GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs10935120 | 1 | rs7433991 | chr3:134312292 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 6.73 | 1.03E-8 | Height |
| UVM | cis | rs2273 | 1 | rs7436021 | chr4:76905472 | NAAA | chr4:76831809-76862166:- | -0.44 | -4.99 | 6.33E-6 | Longevity |
| UVM | cis | rs11190604 | 1 | rs74650218 | chr10:102293830 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs7477246 | chr10:102261538 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs75063298 | chr10:102213600 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs78153629 | 1 | rs75159543 | chr15:40665228 | C15orf23 | chr15:40674922-40686488:+ | 0.92 | 6.6 | 1.72E-8 | Heschl's gyrus morphology |
| UVM | cis | rs1411478 | 1 | rs7516739 | chr1:180948506 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.74 | 4.28E-7 | Progressive supranuclear palsy |
| UVM | cis | rs4660306 | 1 | rs7522705 | chr1:45992300 | CCDC163P | chr1:45960581-45965646:- | 0.76 | 7.78 | 1.99E-10 | Homocysteine levels |
| UVM | cis | rs78153629 | 1 | rs75278386 | chr15:40678312 | C15orf23 | chr15:40674922-40686488:+ | 0.9 | 5.65 | 5.93E-7 | Heschl's gyrus morphology |
| UVM | cis | rs1411478 | 1 | rs7528526 | chr1:180948574 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.74 | 4.28E-7 | Progressive supranuclear palsy |
| UVM | cis | rs4660306 | 1 | rs7534467 | chr1:45988691 | CCDC163P | chr1:45960581-45965646:- | -0.76 | -7.95 | 1.07E-10 | Homocysteine levels |
| UVM | cis | rs4660306 | 1 | rs7536557 | chr1:45992114 | CCDC163P | chr1:45960581-45965646:- | -0.73 | -7.85 | 1.53E-10 | Homocysteine levels |
| UVM | cis | rs1411478 | 1 | rs7553330 | chr1:180956015 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.69 | 5.07E-7 | Progressive supranuclear palsy |
| UVM | cis | rs7581224 | 1 | rs7581224 | chr2:84709215 | DNAH6 | chr2:84743579-85046711:+ | 0.56 | 5.7 | 4.83E-7 | Coronary artery calcification |
| UVM | cis | rs2239557 | 1 | rs75824542 | chr14:74523047 | LIN52 | chr14:74551656-74667117:+ | 0.44 | 5.65 | 5.92E-7 | Common traits (Other) |